Parabon NanoLabs Demonstrates Its Nano-Pharmaceutical
Platform Can Create Artificial Vaccines

31 March 2012

Parabon announced today that it has demonstrated the feasibility of extending its Essemblix Drug Development Platform to produce Essemblix-V, a platform for creating artificial vaccines from a predefined set of "building block molecules" assembled on DNA origami. Given an epitope for a potential biothreat agent, Parabon's Essemblix-V will allow the production of artificial epitopes (hereafter "mimotopes") that can mimic the original epitope sufficiently to bind target antibodies with high affinity. Additionally, Essemblix-V will allow mimotopes to be arranged on origami in complex presentation patterns known to elicit rapid and potent immune response via T cell-independent activation. The effort was funded by the US Department of Defense's Department of Health Program. Parabon has applied for Phase II funding to further enhance, test and commercialize the capability.

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